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MAP1B rescues LRRK2 mutant-mediated cytotoxicity

Leucine-rich repeat kinase 2 (LRRK2) mutations are the most common cause of dominant and sporadic Parkinson’s disease (PD), a common neurodegenerative disorder. Yeast-two-hybrid screening using human LRRK2 kinase domain as bait identified microtubule associated protein 1B (MAP1B) as a LRRK2 interact...

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Detalles Bibliográficos
Autores principales:	Chan, Sharon L, Chua, Ling-Ling, Angeles, Dario C, Tan, Eng-King
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022373/ https://www.ncbi.nlm.nih.gov/pubmed/24754922 http://dx.doi.org/10.1186/1756-6606-7-29

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