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Investigation of the essential role of platelet-tumor cell interactions in metastasis progression using an agent-based model

BACKGROUND: Metastatic tumors are a major source of morbidity and mortality for most cancers. Interaction of circulating tumor cells with endothelium, platelets and neutrophils play an important role in the early stages of metastasis formation. These complex dynamics have proven difficult to study i...

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Detalles Bibliográficos
Autores principales: Uppal, Abhineet, Wightman, Sean C, Ganai, Sabha, Weichselbaum, Ralph R, An, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022382/
https://www.ncbi.nlm.nih.gov/pubmed/24725600
http://dx.doi.org/10.1186/1742-4682-11-17