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Investigation of the essential role of platelet-tumor cell interactions in metastasis progression using an agent-based model
BACKGROUND: Metastatic tumors are a major source of morbidity and mortality for most cancers. Interaction of circulating tumor cells with endothelium, platelets and neutrophils play an important role in the early stages of metastasis formation. These complex dynamics have proven difficult to study i...
Autores principales: | Uppal, Abhineet, Wightman, Sean C, Ganai, Sabha, Weichselbaum, Ralph R, An, Gary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022382/ https://www.ncbi.nlm.nih.gov/pubmed/24725600 http://dx.doi.org/10.1186/1742-4682-11-17 |
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