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Mesenchymal to amoeboid transition is associated with stem-like features of melanoma cells

BACKGROUND: Cellular plasticity confers cancer cells the ability to adapt to microenvironmental changes, a fundamental requirement for tumour progression and metastasis. The epithelial to mesenchymal transition (EMT) is a transcriptional programme associated with increased cell motility and stemness...

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Detalles Bibliográficos
Autores principales: Taddei, Maria Letizia, Giannoni, Elisa, Morandi, Andrea, Ippolito, Luigi, Ramazzotti, Matteo, Callari, Maurizio, Gandellini, Paolo, Chiarugi, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022383/
https://www.ncbi.nlm.nih.gov/pubmed/24690323
http://dx.doi.org/10.1186/1478-811X-12-24