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Effect of novobiocin on the viability of human gingival fibroblasts (HGF-1)
BACKGROUND: Novobiocin is a coumarin antibiotic, which affects also eukaryotic cells inhibiting activity of Heat shock protein 90 (Hsp90). The Hsp90 represents a molecular chaperone critical for stabilization and activation of many proteins, particularly oncoproteins that drive cancer progression. C...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022396/ https://www.ncbi.nlm.nih.gov/pubmed/24887242 http://dx.doi.org/10.1186/2050-6511-15-25 |