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p53 Requires the Stress Sensor USF1 to Direct Appropriate Cell Fate Decision
Genomic instability is a major hallmark of cancer. To maintain genomic integrity, cells are equipped with dedicated sensors to monitor DNA repair or to force damaged cells into death programs. The tumor suppressor p53 is central in this process. Here, we report that the ubiquitous transcription fact...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022457/ https://www.ncbi.nlm.nih.gov/pubmed/24831529 http://dx.doi.org/10.1371/journal.pgen.1004309 |