Genomic Characterization of Large Heterochromatic Gaps in the Human Genome Assembly

The largest gaps in the human genome assembly correspond to multi-megabase heterochromatic regions composed primarily of two related families of tandem repeats, Human Satellites 2 and 3 (HSat2,3). The abundance of repetitive DNA in these regions challenges standard mapping and assembly algorithms, a...

Descripción completa

Detalles Bibliográficos
Autores principales: Altemose, Nicolas, Miga, Karen H., Maggioni, Mauro, Willard, Huntington F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022460/
https://www.ncbi.nlm.nih.gov/pubmed/24831296
http://dx.doi.org/10.1371/journal.pcbi.1003628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022460/
https://www.ncbi.nlm.nih.gov/pubmed/24831296
http://dx.doi.org/10.1371/journal.pcbi.1003628

Ejemplares similares