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A HECT Ubiquitin-Protein Ligase as a Novel Candidate Gene for Altered Quinine and Quinidine Responses in Plasmodium falciparum

The emerging resistance to quinine jeopardizes the efficacy of a drug that has been used in the treatment of malaria for several centuries. To identify factors contributing to differential quinine responses in the human malaria parasite Plasmodium falciparum, we have conducted comparative quantitati...

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Detalles Bibliográficos
Autores principales: Sanchez, Cecilia P., Liu, Chia-Hao, Mayer, Sybille, Nurhasanah, Astutiati, Cyrklaff, Marek, Mu, Jianbing, Ferdig, Michael T., Stein, Wilfred D., Lanzer, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022464/
https://www.ncbi.nlm.nih.gov/pubmed/24830312
http://dx.doi.org/10.1371/journal.pgen.1004382