ATPase Subdomain IA Is a Mediator of Interdomain Allostery in Hsp70 Molecular Chaperones

The versatile functions of the heat shock protein 70 (Hsp70) family of molecular chaperones rely on allosteric interactions between their nucleotide-binding and substrate-binding domains, NBD and SBD. Understanding the mechanism of interdomain allostery is essential to rational design of Hsp70 modul...

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Detalles Bibliográficos
Autores principales: General, Ignacio J., Liu, Ying, Blackburn, Mandy E., Mao, Wenzhi, Gierasch, Lila M., Bahar, Ivet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022485/
https://www.ncbi.nlm.nih.gov/pubmed/24831085
http://dx.doi.org/10.1371/journal.pcbi.1003624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022485/
https://www.ncbi.nlm.nih.gov/pubmed/24831085
http://dx.doi.org/10.1371/journal.pcbi.1003624

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