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Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

Genetic association studies, in particular the genome-wide association study (GWAS) design, have provided a wealth of novel insights into the aetiology of a wide range of human diseases and traits, in particular cardiovascular diseases and lipid biomarkers. The next challenge consists of understandi...

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Detalles Bibliográficos
Autores principales: Giambartolomei, Claudia, Vukcevic, Damjan, Schadt, Eric E., Franke, Lude, Hingorani, Aroon D., Wallace, Chris, Plagnol, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022491/
https://www.ncbi.nlm.nih.gov/pubmed/24830394
http://dx.doi.org/10.1371/journal.pgen.1004383