Deregulation of Microcephalin and ASPM Expression Are Correlated with Epithelial Ovarian Cancer Progression

Mutations in the MCPH1 (Microcephalin) and ASPM (abnormal spindle-like microcephaly associated) genes cause primary microcephaly. Both are centrosomal associated proteins involved in mitosis. Microcephalin plays an important role in DNA damage response and ASPM is required for correct division of pr...

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Detalles Bibliográficos
Autores principales: Alsiary, Rawiah, Brüning-Richardson, Anke, Bond, Jacquelyn, Morrison, Ewan E., Wilkinson, Nafisa, Bell, Sandra M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022499/
https://www.ncbi.nlm.nih.gov/pubmed/24830737
http://dx.doi.org/10.1371/journal.pone.0097059

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022499/
https://www.ncbi.nlm.nih.gov/pubmed/24830737
http://dx.doi.org/10.1371/journal.pone.0097059

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