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Deregulation of Microcephalin and ASPM Expression Are Correlated with Epithelial Ovarian Cancer Progression
Mutations in the MCPH1 (Microcephalin) and ASPM (abnormal spindle-like microcephaly associated) genes cause primary microcephaly. Both are centrosomal associated proteins involved in mitosis. Microcephalin plays an important role in DNA damage response and ASPM is required for correct division of pr...
Autores principales: | Alsiary, Rawiah, Brüning-Richardson, Anke, Bond, Jacquelyn, Morrison, Ewan E., Wilkinson, Nafisa, Bell, Sandra M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022499/ https://www.ncbi.nlm.nih.gov/pubmed/24830737 http://dx.doi.org/10.1371/journal.pone.0097059 |
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