Analysis of rare variations reveals roles of amino acid residues in the N-terminal extracellular domain of nicotinic acetylcholine receptor (nAChR) alpha6 subunit in the functional expression of human alpha6*-nAChRs

BACKGROUND: Functional heterologous expression of naturally-expressed and apparently functional mammalian α6*-nicotinic acetylcholine receptors (nAChRs; where ‘*’ indicates presence of additional subunits) has been difficult. Here we wanted to investigate the role of N-terminal domain (NTD) residues...

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Detalles Bibliográficos
Autores principales: Dash, Bhagirathi, Li, Ming D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022547/
https://www.ncbi.nlm.nih.gov/pubmed/24886653
http://dx.doi.org/10.1186/1756-6606-7-35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022547/
https://www.ncbi.nlm.nih.gov/pubmed/24886653
http://dx.doi.org/10.1186/1756-6606-7-35

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