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Interactions between Exosomes from Breast Cancer Cells and Primary Mammary Epithelial Cells Leads to Generation of Reactive Oxygen Species Which Induce DNA Damage Response, Stabilization of p53 and Autophagy in Epithelial Cells

Exosomes are nanovesicles originating from multivesicular bodies and are released by all cell types. They contain proteins, lipids, microRNAs, mRNAs and DNA fragments, which act as mediators of intercellular communications by inducing phenotypic changes in recipient cells. Tumor-derived exosomes hav...

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Detalles Bibliográficos
Autores principales: Dutta, Sujoy, Warshall, Case, Bandyopadhyay, Chirosree, Dutta, Dipanjan, Chandran, Bala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022578/
https://www.ncbi.nlm.nih.gov/pubmed/24831807
http://dx.doi.org/10.1371/journal.pone.0097580