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Maternal Separation Enhances Conditioned Fear and Decreases the mRNA Levels of the Neurotensin Receptor 1 Gene with Hypermethylation of This Gene in the Rat Amygdala

Stress during postnatal development is associated with an increased risk for depression, anxiety disorders, and substance abuse later in life, almost as if mental illness is able to be programed by early life stressors. Recent studies suggest that such “programmed” effects can be caused by epigeneti...

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Detalles Bibliográficos
Autores principales: Toda, Hiroyuki, Boku, Shuken, Nakagawa, Shin, Inoue, Takeshi, Kato, Akiko, Takamura, Naoki, Song, Ning, Nibuya, Masashi, Koyama, Tsukasa, Kusumi, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022612/
https://www.ncbi.nlm.nih.gov/pubmed/24831231
http://dx.doi.org/10.1371/journal.pone.0097421