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Maternal Separation Enhances Conditioned Fear and Decreases the mRNA Levels of the Neurotensin Receptor 1 Gene with Hypermethylation of This Gene in the Rat Amygdala
Stress during postnatal development is associated with an increased risk for depression, anxiety disorders, and substance abuse later in life, almost as if mental illness is able to be programed by early life stressors. Recent studies suggest that such “programmed” effects can be caused by epigeneti...
Autores principales: | Toda, Hiroyuki, Boku, Shuken, Nakagawa, Shin, Inoue, Takeshi, Kato, Akiko, Takamura, Naoki, Song, Ning, Nibuya, Masashi, Koyama, Tsukasa, Kusumi, Ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022612/ https://www.ncbi.nlm.nih.gov/pubmed/24831231 http://dx.doi.org/10.1371/journal.pone.0097421 |
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