The Tetraspanin CD53 Modulates Responses from Activating NK Cell Receptors, Promoting LFA-1 Activation and Dampening NK Cell Effector Functions

NK cells express several tetraspanin proteins, which differentially modulate NK cell activities. The tetraspanin CD53 is expressed by all resting NK cells and was previously shown to decrease NK cell cytotoxicity upon ligation. Here, we show that CD53 ligation reduced degranulation of rat NK cells i...

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Detalles Bibliográficos
Autores principales: Todros-Dawda, Izabela, Kveberg, Lise, Vaage, John T., Inngjerdingen, Marit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022634/
https://www.ncbi.nlm.nih.gov/pubmed/24832104
http://dx.doi.org/10.1371/journal.pone.0097844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022634/
https://www.ncbi.nlm.nih.gov/pubmed/24832104
http://dx.doi.org/10.1371/journal.pone.0097844

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