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Tubulin Binds to the Cytoplasmic Loop of TRESK Background K(+) Channel In Vitro
The cytoplasmic loop between the second and third transmembrane segments is pivotal in the regulation of TRESK (TWIK-related spinal cord K(+) channel, K2P18.1, KCNK18). Calcineurin binds to this region and activates the channel by dephosphorylation in response to the calcium signal. Phosphorylation-...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022642/ https://www.ncbi.nlm.nih.gov/pubmed/24830385 http://dx.doi.org/10.1371/journal.pone.0097854 |