Human Hsp60 with Its Mitochondrial Import Signal Occurs in Solution as Heptamers and Tetradecamers Remarkably Stable over a Wide Range of Concentrations

It has been established that Hsp60 can accumulate in the cytosol in various pathological conditions, including cancer and chronic inflammatory diseases. Part or all of the cytosolic Hsp60 could be naïve, namely, bear the mitochondrial import signal (MIS), but neither the structure nor the in solutio...

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Detalles Bibliográficos
Autores principales: Vilasi, Silvia, Carrotta, Rita, Mangione, Maria Rosalia, Campanella, Claudia, Librizzi, Fabio, Randazzo, Loredana, Martorana, Vincenzo, Marino Gammazza, Antonella, Ortore, Maria Grazia, Vilasi, Annalisa, Pocsfalvi, Gabriella, Burgio, Giosalba, Corona, Davide, Palumbo Piccionello, Antonio, Zummo, Giovanni, Bulone, Donatella, Conway de Macario, Everly, Macario, Alberto J. L., San Biagio, Pier Luigi, Cappello, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022648/
https://www.ncbi.nlm.nih.gov/pubmed/24830947
http://dx.doi.org/10.1371/journal.pone.0097657

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022648/
https://www.ncbi.nlm.nih.gov/pubmed/24830947
http://dx.doi.org/10.1371/journal.pone.0097657

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