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Striking Differences between Knockout and Wild-Type Mice in Global Gene Expression Variability

Microarray analyses of gene knockouts have traditionally focused on the identification of genes whose mean expression is different in knockout and wild-type mice. However, recent work suggests that changes in the variability of gene expression can have important phenotypic consequences as well. Here...

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Detalles Bibliográficos
Autor principal: Eraly, Satish A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022672/
https://www.ncbi.nlm.nih.gov/pubmed/24830645
http://dx.doi.org/10.1371/journal.pone.0097734