Papillomavirus Genomes Associate with BRD4 to Replicate at Fragile Sites in the Host Genome

It has long been recognized that oncogenic viruses often integrate close to common fragile sites. The papillomavirus E2 protein, in complex with BRD4, tethers the viral genome to host chromatin to ensure persistent replication. Here, we map these targets to a number of large regions of the human gen...

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Detalles Bibliográficos
Autores principales: Jang, Moon Kyoo, Shen, Kui, McBride, Alison A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022725/
https://www.ncbi.nlm.nih.gov/pubmed/24832099
http://dx.doi.org/10.1371/journal.ppat.1004117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022725/
https://www.ncbi.nlm.nih.gov/pubmed/24832099
http://dx.doi.org/10.1371/journal.ppat.1004117

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