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Mycobacterium tuberculosis Hip1 Modulates Macrophage Responses through Proteolysis of GroEL2
Mycobacterium tuberculosis (Mtb) employs multiple strategies to evade host immune responses and persist within macrophages. We have previously shown that the cell envelope-associated Mtb serine hydrolase, Hip1, prevents robust macrophage activation and dampens host pro-inflammatory responses, allowi...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022732/ https://www.ncbi.nlm.nih.gov/pubmed/24830429 http://dx.doi.org/10.1371/journal.ppat.1004132 |