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Effects of Brilliant Blue G on Serum Tumor Necrosis Factor-α Levels and Depression-like Behavior in Mice after Lipopolysaccharide Administration

OBJECTIVE: Accumulating evidence suggests that inflammation plays a role in the pathophysiology of major depression. The adenosine triphosphate (ATP)-sensitive P2X7 receptor (P2X7R) plays a crucial role in microglial activation caused by inflammation. The dye brilliant blue G (BBG) is a P2X7R antago...

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Detalles Bibliográficos
Autores principales: Ma, Min, Ren, Qian, Zhang, Ji-chun, Hashimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean College of Neuropsychopharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022763/
https://www.ncbi.nlm.nih.gov/pubmed/24851118
http://dx.doi.org/10.9758/cpn.2014.12.1.31