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The Nuclear Orphan Receptor NR4A1 is Involved in the Apoptotic Pathway Induced by LPS and Simvastatin in RAW 264.7 Macrophages

Macrophage death plays a role in several physiological and inflammatory pathologies such as sepsis and arthritis. In our previous work, we showed that simvastatin triggers cell death in LPS-activated RAW 264.7 mouse macrophage cells through both caspase-dependent and independent apoptotic pathways....

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Detalles Bibliográficos
Autores principales: Kim, Yong Chan, Song, Seok Bean, Lee, Sang Kyu, Park, Sang Min, Kim, Young Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022779/
https://www.ncbi.nlm.nih.gov/pubmed/24851101
http://dx.doi.org/10.4110/in.2014.14.2.116