Phosphorylation of the Proapoptotic BH3-Only Protein Bid Primes Mitochondria for Apoptosis during Mitotic Arrest

Mitosis is a moment of exquisite vulnerability for a metazoan cell. Failure to complete mitosis accurately can lead to aneuploidy and cancer initiation. Therefore, if the exit from mitosis is delayed, normal cells are usually removed by apoptosis. However, how failure to complete mitosis activates a...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Pengbo, Lindsay, Jennefer, Owens, Thomas W., Mularczyk, Ewa J., Warwood, Stacey, Foster, Fiona, Streuli, Charles H., Brennan, Keith, Gilmore, Andrew P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022835/
https://www.ncbi.nlm.nih.gov/pubmed/24767991
http://dx.doi.org/10.1016/j.celrep.2014.03.050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022835/
https://www.ncbi.nlm.nih.gov/pubmed/24767991
http://dx.doi.org/10.1016/j.celrep.2014.03.050

Ejemplares similares