Dynorphin Acts as a Neuromodulator to Inhibit Itch in the Dorsal Horn of the Spinal Cord

Menthol and other counterstimuli relieve itch, resulting in an antipruritic state that persists for minutes to hours. However, the neural basis for this effect is unclear, and the underlying neuromodulatory mechanisms are unknown. Previous studies revealed that Bhlhb5(−/−) mice, which lack a specifi...

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Detalles Bibliográficos
Autores principales: Kardon, Adam P., Polgár, Erika, Hachisuka, Junichi, Snyder, Lindsey M., Cameron, Darren, Savage, Sinead, Cai, Xiaoyun, Karnup, Sergei, Fan, Christopher R., Hemenway, Gregory M., Bernard, Carcha S., Schwartz, Erica S., Nagase, Hiroshi, Schwarzer, Christoph, Watanabe, Masahiko, Furuta, Takahiro, Kaneko, Takeshi, Koerber, H. Richard, Todd, Andrew J., Ross, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022838/
https://www.ncbi.nlm.nih.gov/pubmed/24726382
http://dx.doi.org/10.1016/j.neuron.2014.02.046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022838/
https://www.ncbi.nlm.nih.gov/pubmed/24726382
http://dx.doi.org/10.1016/j.neuron.2014.02.046

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