Fragments of Bacterial Endoglycosidase S and Immunoglobulin G Reveal Subdomains of Each That Contribute to Deglycosylation

Endoglycosidase S (EndoS) is a glycoside-hydrolase secreted by the bacterium Streptococcus pyogenes. EndoS preferentially hydrolyzes the N-linked glycans from the Fc region of IgG during infection. This hydrolysis impedes Fc functionality and contributes to the immune evasion strategy of S. pyogenes...

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Detalles Bibliográficos
Autores principales: Dixon, Emma V., Claridge, Jolyon K., Harvey, David J., Baruah, Kavitha, Yu, Xiaojie, Vesiljevic, Snezana, Mattick, Susan, Pritchard, Laura K., Krishna, Benjamin, Scanlan, Christopher N., Schnell, Jason R., Higgins, Matthew K., Zitzmann, Nicole, Crispin, Max
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Glycobiology and Extracellular Matrices
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022860/
https://www.ncbi.nlm.nih.gov/pubmed/24668806
http://dx.doi.org/10.1074/jbc.M113.532812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4022860/
https://www.ncbi.nlm.nih.gov/pubmed/24668806
http://dx.doi.org/10.1074/jbc.M113.532812

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