A functional screen for copper homeostasis genes identifies a pharmacologically tractable cellular system

BACKGROUND: Copper is essential for the survival of aerobic organisms. If copper is not properly regulated in the body however, it can be extremely cytotoxic and genetic mutations that compromise copper homeostasis result in severe clinical phenotypes. Understanding how cells maintain optimal copper...

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Detalles Bibliográficos
Autores principales: Schlecht, Ulrich, Suresh, Sundari, Xu, Weihong, Aparicio, Ana Maria, Chu, Angela, Proctor, Michael J, Davis, Ronald W, Scharfe, Curt, St Onge, Robert P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023593/
https://www.ncbi.nlm.nih.gov/pubmed/24708151
http://dx.doi.org/10.1186/1471-2164-15-263

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023593/
https://www.ncbi.nlm.nih.gov/pubmed/24708151
http://dx.doi.org/10.1186/1471-2164-15-263

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