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Altering gene expression by aminocoumarins: the role of DNA supercoiling in Staphylococcus aureus
BACKGROUND: It has been shown previously that aminocoumarin antibiotics such as novobiocin lead to immediate downregulation of recA expression and thereby inhibit the SOS response, mutation frequency and recombination capacity in Staphylococcus aureus. Aminocoumarins function by inhibiting the ATPas...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023603/ https://www.ncbi.nlm.nih.gov/pubmed/24734910 http://dx.doi.org/10.1186/1471-2164-15-291 |