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Altering gene expression by aminocoumarins: the role of DNA supercoiling in Staphylococcus aureus

BACKGROUND: It has been shown previously that aminocoumarin antibiotics such as novobiocin lead to immediate downregulation of recA expression and thereby inhibit the SOS response, mutation frequency and recombination capacity in Staphylococcus aureus. Aminocoumarins function by inhibiting the ATPas...

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Detalles Bibliográficos
Autores principales:	Schröder, Wiebke, Bernhardt, Jörg, Marincola, Gabriella, Klein-Hitpass, Ludger, Herbig, Alexander, Krupp, Guido, Nieselt, Kay, Wolz, Christiane
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023603/ https://www.ncbi.nlm.nih.gov/pubmed/24734910 http://dx.doi.org/10.1186/1471-2164-15-291

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