Golgi fragmentation precedes neuromuscular denervation and is associated with endosome abnormalities in SOD1-ALS mouse motor neurons

BACKGROUND: Fragmentation of stacked cisterns of the Golgi apparatus into dispersed smaller elements is a feature associated with degeneration of neurons in amyotrophic lateral sclerosis (ALS) and some other neurodegenerative disorders. However, the role of Golgi fragmentation in motor neuron degene...

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Detalles Bibliográficos
Autores principales: van Dis, Vera, Kuijpers, Marijn, Haasdijk, Elize D, Teuling, Eva, Oakes, Scott A, Hoogenraad, Casper C, Jaarsma, Dick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023628/
https://www.ncbi.nlm.nih.gov/pubmed/24708899
http://dx.doi.org/10.1186/2051-5960-2-38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023628/
https://www.ncbi.nlm.nih.gov/pubmed/24708899
http://dx.doi.org/10.1186/2051-5960-2-38

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