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NOTCH ligands JAG1 and JAG2 as critical pro-survival factors in childhood medulloblastoma
Medulloblastoma (MB), the most common pediatric malignant brain cancer, typically arises as pathological result of deregulated developmental pathways, including the NOTCH signaling cascade. Unlike the evidence supporting a role for NOTCH receptors in MB development, the pathological functions of NOT...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023630/ https://www.ncbi.nlm.nih.gov/pubmed/24708907 http://dx.doi.org/10.1186/2051-5960-2-39 |