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edgeR: a versatile tool for the analysis of shRNA-seq and CRISPR-Cas9 genetic screens

Pooled library sequencing screens that perturb gene function in a high-throughput manner are becoming increasingly popular in functional genomics research. Irrespective of the mechanism by which loss of function is achieved, via either RNA interference using short hairpin RNAs (shRNAs) or genetic mu...

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Detalles Bibliográficos
Autores principales: Dai, Zhiyin, Sheridan, Julie M., Gearing, Linden J., Moore, Darcy L., Su, Shian, Wormald, Sam, Wilcox, Stephen, O'Connor, Liam, Dickins, Ross A., Blewitt, Marnie E., Ritchie, Matthew E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023662/
https://www.ncbi.nlm.nih.gov/pubmed/24860646
http://dx.doi.org/10.12688/f1000research.3928.2