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edgeR: a versatile tool for the analysis of shRNA-seq and CRISPR-Cas9 genetic screens
Pooled library sequencing screens that perturb gene function in a high-throughput manner are becoming increasingly popular in functional genomics research. Irrespective of the mechanism by which loss of function is achieved, via either RNA interference using short hairpin RNAs (shRNAs) or genetic mu...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
F1000Research
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023662/ https://www.ncbi.nlm.nih.gov/pubmed/24860646 http://dx.doi.org/10.12688/f1000research.3928.2 |