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Mitochondrial response to nutrient availability and its role in metabolic disease

Metabolic inflexibility is defined as an impaired capacity to switch between different energy substrates and is a hallmark of insulin resistance and type 2 diabetes mellitus (T2DM). Hence, understanding the mechanisms underlying proper metabolic flexibility is key to prevent the development of metab...

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Detalles Bibliográficos
Autores principales: Gao, Arwen W, Cantó, Carles, Houtkooper, Riekelt H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023882/
https://www.ncbi.nlm.nih.gov/pubmed/24623376
http://dx.doi.org/10.1002/emmm.201303782