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Local acting Sticky-trap inhibits vascular endothelial growth factor dependent pathological angiogenesis in the eye

Current therapeutic antiangiogenic biologics used for the treatment of pathological ocular angiogenesis could have serious side effects due to their interference with normal blood vessel physiology. Here, we report the generation of novel antivascular endothelial growth factor-A (VEGF) biologics, te...

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Detalles Bibliográficos
Autores principales: Michael, Iacovos P, Westenskow, Peter D, Hacibekiroglu, Sabiha, Greenwald, Alissa Cohen, Ballios, Brian G, Kurihara, Toshihide, Li, Zhijie, Warren, Carmen M, Zhang, Puzheng, Aguilar, Edith, Donaldson, Laura, Marchetti, Valentina, Baba, Takeshi, Hussein, Samer M, Sung, Hoon-Ki, Iruela-Arispe, M Luisa, Rini, James M, van der Kooy, Derek, Friedlander, Martin, Nagy, Andras
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023884/
https://www.ncbi.nlm.nih.gov/pubmed/24705878
http://dx.doi.org/10.1002/emmm.201303708