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An RNA Aptamer That Specifically Binds to the Glycosylated Hemagglutinin of Avian Influenza Virus and Suppresses Viral Infection in Cells

The influenza virus surface glycoprotein hemagglutinin (HA) is responsible for viral attachment to sialic acid-containing host cell receptors and it facilitates the initial stage of viral infection. In the present study, we isolated an RNA aptamer specific to the glycosylated receptor-binding domain...

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Detalles Bibliográficos
Autores principales: Kwon, Hyun-Mi, Lee, Kwang Hyun, Han, Byung Woo, Han, Mi Ra, Kim, Dong Ho, Kim, Dong-Eun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023947/
https://www.ncbi.nlm.nih.gov/pubmed/24835440
http://dx.doi.org/10.1371/journal.pone.0097574