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Formaldehyde-Assisted Isolation of Regulatory Elements (FAIRE) Analysis Uncovers Broad Changes in Chromatin Structure Resulting from Hexavalent Chromium Exposure

The ability of chromatin to switch back and forth from open euchromatin to closed heterochromatin is vital for transcriptional regulation and genomic stability, but its dynamic structure is subject to disruption by exposure to environmental agents such as hexavalent chromium. Cr(VI) exposure disrupt...

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Detalles Bibliográficos
Autores principales: Ovesen, Jerald L., Fan, Yunxia, Zhang, Xiang, Chen, Jing, Medvedovic, Mario, Xia, Ying, Puga, Alvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023961/
https://www.ncbi.nlm.nih.gov/pubmed/24837440
http://dx.doi.org/10.1371/journal.pone.0097849