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Formaldehyde-Assisted Isolation of Regulatory Elements (FAIRE) Analysis Uncovers Broad Changes in Chromatin Structure Resulting from Hexavalent Chromium Exposure
The ability of chromatin to switch back and forth from open euchromatin to closed heterochromatin is vital for transcriptional regulation and genomic stability, but its dynamic structure is subject to disruption by exposure to environmental agents such as hexavalent chromium. Cr(VI) exposure disrupt...
Autores principales: | Ovesen, Jerald L., Fan, Yunxia, Zhang, Xiang, Chen, Jing, Medvedovic, Mario, Xia, Ying, Puga, Alvaro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023961/ https://www.ncbi.nlm.nih.gov/pubmed/24837440 http://dx.doi.org/10.1371/journal.pone.0097849 |
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