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Common Contaminants in Next-Generation Sequencing That Hinder Discovery of Low-Abundance Microbes
Unbiased high-throughput sequencing of whole metagenome shotgun DNA libraries is a promising new approach to identifying microbes in clinical specimens, which, unlike other techniques, is not limited to known sequences. Unlike most sequencing applications, it is highly sensitive to laboratory contam...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4023998/ https://www.ncbi.nlm.nih.gov/pubmed/24837716 http://dx.doi.org/10.1371/journal.pone.0097876 |