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Detection of driver metabolites in the human liver metabolic network using structural controllability analysis
BACKGROUND: Abnormal states in human liver metabolism are major causes of human liver diseases ranging from hepatitis to hepatic tumor. The accumulation in relevant data makes it feasible to derive a large-scale human liver metabolic network (HLMN) and to discover important biological principles or...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024020/ https://www.ncbi.nlm.nih.gov/pubmed/24885538 http://dx.doi.org/10.1186/1752-0509-8-51 |