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Long Bone Structure and Strength Depend on BMP2 from Osteoblasts and Osteocytes, but Not Vascular Endothelial Cells

The importance of bone morphogenetic protein 2 (BMP2) in the skeleton is well known. BMP2 is expressed in a variety of tissues during development, growth and healing. In this study we sought to better identify the role of tissue-specific BMP2 during post-natal growth and to determine if BMP2 knockou...

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Detalles Bibliográficos
Autores principales: McBride, Sarah H., McKenzie, Jennifer A., Bedrick, Bronwyn S., Kuhlmann, Paige, Pasteris, Jill D., Rosen, Vicki, Silva, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024030/
https://www.ncbi.nlm.nih.gov/pubmed/24837969
http://dx.doi.org/10.1371/journal.pone.0096862