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Tumor-associated macrophage-derived IL-6 and IL-8 enhance invasive activity of LoVo cells induced by PRL-3 in a KCNN4 channel-dependent manner

BACKGROUND: Tumor-associated macrophages (TAMs) are known to promote cancer progression and metastasis through the release of a variety of cytokines. Phosphatase of regenerating liver (PRL-3) has been considered as a marker of colorectal cancer (CRC) liver metastasis. Our previous research suggests...

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Detalles Bibliográficos
Autores principales: Xu, Heyang, Lai, Wei, Zhang, Yang, Liu, Lu, Luo, Xingxi, Zeng, Yujie, Wu, Heng, Lan, Qiusheng, Chu, Zhonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024187/
https://www.ncbi.nlm.nih.gov/pubmed/24885636
http://dx.doi.org/10.1186/1471-2407-14-330