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High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology()

Obesity and consumption of a high-fat diet are known to increase the risk of Alzheimer's disease (AD). Diets high in fat also increase disease neuropathology and/or cognitive deficits in AD mouse models. However, the effect of a high-fat diet on both the neuropathology and memory impairments in...

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Detalles Bibliográficos
Autores principales: Knight, Elysse M., Martins, Isaura V.A., Gümüsgöz, Sarah, Allan, Stuart M., Lawrence, Catherine B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024197/
https://www.ncbi.nlm.nih.gov/pubmed/24630364
http://dx.doi.org/10.1016/j.neurobiolaging.2014.02.010