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Assessment of Mutational Load in Biopsy Tissue Provides Additional Information About Genomic Instability to Histological Classifications of Barrett's Esophagus

PURPOSE: Progression of Barrett's esophagus (BE) to esophageal adenocarcinoma (EAC) is associated with accumulated genomic instability. Current risk stratification of BE for EAC relies on histological classification and grade of dysplasia. However, histology alone cannot assess the risk of pati...

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Detalles Bibliográficos
Autores principales: Khara, Harshit S., Jackson, Sara A., Nair, Saraswathi, Deftereos, Georgios, Patel, Shweta, Silverman, Jan F., Ellsworth, Eric, Sumner, Cameron, Corcoran, Brendan, Smith, Dennis M., Finkelstein, Sydney, Gross, Seth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024388/
https://www.ncbi.nlm.nih.gov/pubmed/24402860
http://dx.doi.org/10.1007/s12029-013-9570-y