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Elastase and Cathepsin G from Primed Leukocytes Cleave Vascular Endothelial Cadherin in Hemodialysis Patients

Aims. To test the hypothesis that primed PMNLs in blood of chronic kidney disease patients release the active form of elastase and cathepsin G causing degradation of vital proteins and promote tissue damage. Methods. RT-PCR, immunocytochemical staining, immunoblotting, and FACS analyses were used to...

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Detalles Bibliográficos
Autores principales: Cohen-Mazor, Meital, Mazor, Rafi, Kristal, Batya, Sela, Shifra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024418/
https://www.ncbi.nlm.nih.gov/pubmed/24877096
http://dx.doi.org/10.1155/2014/459640