MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degeneration

Subsets of rodent neurons are reported to express major histocompatibilty complex class I (MHC-I), but such expression has not been reported in normal adult human neurons. Here we provide evidence from immunolabel, RNA expression, and mass spectrometry analysis of postmortem samples that human catec...

Descripción completa

Detalles Bibliográficos
Autores principales: Cebrián, Carolina, Zucca, Fabio A., Mauri, Pierluigi, Steinbeck, Julius A., Studer, Lorenz, Scherzer, Clemens R., Kanter, Ellen, Budhu, Sadna, Mandelbaum, Jonathan, Vonsattel, Jean P., Zecca, Luigi, Loike, John D., Sulzer, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024461/
https://www.ncbi.nlm.nih.gov/pubmed/24736453
http://dx.doi.org/10.1038/ncomms4633

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024461/
https://www.ncbi.nlm.nih.gov/pubmed/24736453
http://dx.doi.org/10.1038/ncomms4633

Ejemplares similares