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Epistasis and Natural Selection Shape the Mutational Architecture of Complex Traits

The evolutionary trajectories of complex traits are constrained by levels of genetic variation as well as genetic correlations among traits. Because the ultimate source of all genetic variation is mutation, the distribution of mutations entering populations profoundly affects standing variation and...

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Detalles Bibliográficos
Autores principales: Jones, Adam G., Bürger, Reinhard, Arnold, Stevan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024485/
https://www.ncbi.nlm.nih.gov/pubmed/24828461
http://dx.doi.org/10.1038/ncomms4709