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Epistasis and Natural Selection Shape the Mutational Architecture of Complex Traits
The evolutionary trajectories of complex traits are constrained by levels of genetic variation as well as genetic correlations among traits. Because the ultimate source of all genetic variation is mutation, the distribution of mutations entering populations profoundly affects standing variation and...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024485/ https://www.ncbi.nlm.nih.gov/pubmed/24828461 http://dx.doi.org/10.1038/ncomms4709 |