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Mining of public sequencing databases supports a non-dietary origin for putative foreign miRNAs: underestimated effects of contamination in NGS

The report that exogenous plant miRNAs are able to cross the mammalian gastrointestinal tract and exert gene-regulation mechanism in mammalian tissues has yielded a lot of controversy, both in the public press and the scientific literature. Despite the initial enthusiasm, reproducibility of these re...

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Detalles Bibliográficos
Autores principales: Tosar, Juan Pablo, Rovira, Carlos, Naya, Hugo, Cayota, Alfonso
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4024629/
https://www.ncbi.nlm.nih.gov/pubmed/24729469
http://dx.doi.org/10.1261/rna.044263.114